Pegaspargase: A Review in Acute Lymphoblastic Leukaemia
نویسندگان
چکیده
منابع مشابه
A Review on Acute Lymphoblastic Leukaemia
Introduction he leukaemias are malignant neoplasms of the haemopoietic stem cells. 1 acute leukaemia is the most common malignancy in children. 2 In the United States the incidence of ALL is roughly 6000 new cases per year (as of 2009), or approximately 1 in 50,000. 3 Acute lymphoblastic leukaemia makes up three quarters of all cases of leukaemia in children and 20% of all cases of leukaemia in...
متن کاملAcute Lymphoblastic Leukaemia
Acute lymphoblastic leukaemia (ALL) is a malignant transformation of a clone of cells from lymphoid progenitor cells. The majority of cases are of B-cell origin but it can also arise from T-cell precursors. Lymphoid precursors proliferate and replace the normal cells of the bone marrow and blasts spill into the peripheral circulation. It can be distinguished from other malignancies of lymphoid ...
متن کاملAcute Lymphoblastic Leukaemia
Acute lymphoblastic leukaemia (ALL) is a malignant transformation of a clone of cells from lymphoid progenitor cells. The majority of cases are of B-cell origin but it can also arise from T-cell precursors. Lymphoid precursors proliferate and replace the normal cells of the bone marrow and blasts spill into the peripheral circulation. It can be distinguished from other malignancies of lymphoid ...
متن کاملAcute lymphoblastic leukaemia.
Acute lymphoblastic leukaemia, a malignant disorder of lymphoid progenitor cells, affects both children and adults, with peak prevalence between the ages of 2 and 5 years. Steady progress in development of effective treatments has led to a cure rate of more than 80% in children, creating opportunities for innovative approaches that would preserve past gains in leukaemia-free survival while redu...
متن کاملInfections in acute lymphoblastic leukaemia.
We did a retrospective study of all acute lymphoblastic leukaemia (ALL) patients on United Kingdom ALL protocol who were admitted for febrile neutropenia. The aim of the study was to document the types of infections and aetiological agents associated with febrile neutropenia and to document the factors affecting mortality. Over the 8 1/2-year period from 1986 to June 1995, there were 77 episode...
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ژورنال
عنوان ژورنال: Drugs
سال: 2019
ISSN: 0012-6667,1179-1950
DOI: 10.1007/s40265-019-01120-1